DNA replication is a fundamental process for a cell to ensure that an accurate copy of its genetic material is transmitted to daughter cells at each cell division. Challenges to DNA replication ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

The researchers suspect that 55LCC may be involved in regulating not just the DNA replication process associated with cell division, but also when DNA damaging lesions block replication. Discover the ...